1380341-06-9Relevant academic research and scientific papers
Ni(II)-Catalyzed Enantioselective Synthesis of β-Hydroxy Esters with Carboxylate Assistance
Wang, Na,Liu, Hongxin,Gao, Hang,Zhou, Jiafeng,Zheng, Longzhangdi,Li, Juan,Xiao, Hong-Ping,Li, Xinhua,Jiang, Jun
, p. 6684 - 6689 (2019)
A Ni-oxazoline complex-catalyzed asymmetric decarboxylative aldol reaction between malonic acid half-oxyesters and various carbonyls with carboxylate assistance was developed, affording structurally diverse β-hydroxy esters with good yields and enantioselectivities under mild conditions. Importantly, the broad substrate scope of this methodology enabled rapid accesses to several natural products and their analogues as exemplified by phenylpropanoid, phaitanthrin B, and phthalide.
Synthesizing method of chiral beta hydroxyl acid ester compound
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Paragraph 0072; 0073; 0074; 0075; 0076; 0136-0137, (2019/05/21)
The invention discloses a synthesizing method of a chiral beta hydroxyl acid ester compound. The synthesizing method is characterized by including: subjecting an aldehyde compound and monoalkyl malonate serving as the raw materials to direct and sufficien
