1380346-97-3

Upstream product

• 621-37-4 m-hydroxyphenylacetic acid 
• 1380347-14-7 dimethyl (3-[3-(1-benzofuran-2-yl)phenyl]-2-oxopropyl)phosphonate 
• 1380347-25-0 2-[3-(1-benzofuran-2-yl)phenyl]-N-methoxy-N-methylacetamide 
• 1344214-04-5 2-(3-hydroxyphenyl)-N-methoxy-N-methylacetamide 
• 494224-49-6 (R)-ethyl 4-(tert-butoxycarbonylamino)-5-oxopentanoate 

Downstream Products

• 1380346-98-4 ethyl 2-((2-[(2R)-2-((1E,3S)-4-[3-(1-benzofuran-2-yl)phenyl]-3-hydroxy-1-buten-1-yl)-5-oxo-1-pyrrolidinyl]ethyl) thio)-1,3-thiazole-4-carboxylate 
• 1393523-60-8 C₂₄H₂₇NO₄*ClH 
• 494223-92-6 2-([2-((2R)-2-((1E,3S)-4-[3-(1-benzofuran-2-yl)phenyl]-3-hydroxybut-1-enyl)-5-oxopyrrolidin-1-yl)ethyl]sulfanyl)-1,3-thiazole-4-carboxylic acid 
• 1380346-99-5 ethyl 4-((2-[(2R)-2-((1E,3S)-4-[3-(1-benzofuran-2-yl)phenyl]-3-hydroxy-1-buten-1-yl)-5-oxo-1-pyrrolidinyl]ethyl)thio)butanoate 
• 494223-70-0 4-([2-((2R)-2-((1E,3S)-4-[3-(1-benzofuran-2-yl)phenyl]-3-hydroxybut-1-enyl)-5-oxopyrrolidin-1-yl)ethyl]sulfanyl)butanoic acid 

Relevant academic research and scientific papers

Synthesis and evaluation of γ-lactam analogs of PGE2 as EP4 and EP2/EP4 agonists

To identify topically effective EP4 agonists and EP2/EP4 dual agonists with excellent subtype selectivity, further optimization of the 16-phenyl ω-chain moiety of the γ-lactam 5-thia prostaglandin E analog and the 2-mercaptothiazole-4-carboxylic acid anal