138037-94-2Relevant academic research and scientific papers
A new chiral phosphine oxide ligand for enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides
Eroeksuez, Serap,Dogan, Oezdemir,Garner, Philip P.
, p. 2535 - 2541 (2010)
A new set of phosphorus-containing chiral ligands has been synthesized and used with silver(I) for the catalytic asymmetric 1,3-dipolar cycloaddition reaction of azomethine ylides. One of these ligands (POFAM6) was found to produce an effective catalyst f
Ag(I)/CAAA-Amidphos Complex Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Acrylates for the Formal Synthesis of (+)-Ibophyllidine
Wang, Haifei,Gong, Chuliang,Zhang, Chen,Zheng, Xiaojun,Hou, Qinglin,Zhou, Qingxia,Zhou, Guiyin,Chen, Yao
supporting information, p. 1437 - 1446 (2021/07/17)
In this work, we introduced a multifunctional Ag(I)/CAAA-amidphos complex catalyzed asymmetric 1,3-dipolar cycloaddition of acrylates with α-imino esters, affording a series of 2,4,5-trisubstituted endo -pyrrolidines in good yields (up to 97%) with high enantioselectivities (up to 98% ee). Meanwhile, the catalytic system was also applied in the three-component one-pot reaction of α-imino esters formed in situ under the action of N,N ′-diisopropylcarbodiimide. In addition, the gram-scale reaction was realized for the formal synthesis of (+)-ibophyllidine in eight steps.
Ag/ThioClickFerrophos catalyzed highly enantioselective 1,3-dipolar cycloaddition of azomethine ylides with alkenes
Shimizu, Kenta,Ogata, Kenichi,Fukuzawa, Shin-Ichi
experimental part, p. 5068 - 5070 (2011/01/04)
A silver(I)/ThioClickFerrophos complex catalyzed the endo selective asymmetric 1,3-dipolar cycloaddition reaction of methyl N-benzylideneglycinate (the source of azomethine ylides) with α,β-unsaturated esters and maleimides to give the endo-2,4,5- and 2,3,4,5-substituted pyrrolidines in good yields with high enantioselectivities (up to 99% ee). The complex also effectively catalyzed the endo selective reactions with β-nitrostyrene to give the 4-nitropyrrolidine in a high enantioselectivity.
Chiral Co(II) and Mn(II) catalysts for the 1,3-dipolar cycloaddition reactions of azomethine ylides derived from arylidene imines of glycine
Allway,Grigg
, p. 5817 - 5820 (2007/10/02)
Anhydrous MnBr2 and CoCl2 in conjunction with chiral ephedrine ligands effect substantial asymmetric induction in cycloadducts derived from methyl acrylate and imines of glycine methyl ester. CoCl2 is most effective and gi
