138040-06-9

Upstream product

• 138040-05-8 3-hydroxy-2-(2-nitrophenyl)cyclohex-2-enone 
• 106-95-6 allyl bromide 
• 504-02-9 1,3-cylohexanedione 
• 609-73-4 o-nitroiodobenzene 
• 1493-27-2 ortho-nitrofluorobenzene 
• 30182-67-3 1,3-Cyclohexanedione 

Downstream Products

• 466-85-3 (17R,19E)-17,18-epoxy-cur-19-en-17-ol 
• 57-24-9 strychnidin-10-one 
• 192431-33-7 (3aR,7aS)-N-[(S)-α-Methylbenzyl]-3a-(2-nitrophenyl)octahydroindol-4-one 
• 222162-00-7 (3aR,7aS)-3a-(2-Nitro-phenyl)-4-oxo-2,3,3a,4,7,7a-hexahydro-indole-1-carboxylic acid 1-chloro-ethyl ester 
• 192431-42-8 (3aR,7aS)-3a-(2-Nitro-phenyl)-4-oxo-octahydro-indole-1-carboxylic acid 1-chloro-ethyl ester 
• 222162-02-9 (1R,7R,8S)-2-{(E)-2-[(tert-Butyldimethylsilyl)oxy]ethylidene}-7-(2-nitrophenyl)-4-azatricyclo[5.2.2.0^4,8]undecan-11-one 
• 222162-01-8 (3aR,7aS)-1-{(Z)-4-[(tert-Butyldimethylsilyl)oxy]-2-iodo-2-butenyl}-3a-(2-nitrophenyl)-1,2,3,3a,7,7a-hexahydroindol-4-one 
• 138040-08-1 trans-1-methyl-3a-(o-nitrophenyl)octahydroindol-4-one 
• 138040-08-1 (3aS,7aR)-1-Methyl-3a-(2-nitro-phenyl)-octahydro-indol-4-one 
• 138040-10-5 trans-1-benzyl-3a-(o-nitrophenyl)octahydroindol-4-one 
• 138040-10-5 cis-1-benzyl-3a-(o-nitrophenyl)octahydroindol-4-one 
• 138040-33-2 (3aS,7aR)-3a-(2-Nitro-phenyl)-1-((R)-1-phenyl-ethyl)-octahydro-indol-4-one 
• 138040-34-3 (3aS,7aS)-3a-(2-Nitro-phenyl)-1-((R)-1-phenyl-ethyl)-octahydro-indol-4-one 
• 138040-15-0 (3aR,7aR)-3a-(2-Nitro-phenyl)-1-((R)-1-phenyl-ethyl)-octahydro-indol-4-one 

Relevant academic research and scientific papers

Total synthesis of (-)-strychnine via the Wieland - Gumlich aldehyde

Fifteen steps suffice for an enantioselective total synthesis of (-)- strychnine (1) from 1,3-cyclohexanedione. The key steps are the easy generation of the enantiopure intermediate 2, the closure of the piperidine ring by a reductive Heck reaction, and the elaboration of the indoline nucleus in an advanced synthetic stage. TBDMS = tert-butyldimethylsilyl.

3a-(o-nitrophenyl)octahydroindol-4-ones: Synthesis and spectroscopic analysis

A short entry to 3a-(o-nitrophenyl)octahydroindol-4-ones employing ozonolysis and double reductive amination of 2-allyl-2-(o-nitrophenyl)-1,3-cyclohexanedione (9) is described. The symmetric dione 9 is synthesized in a 50% overall yield from 1,3-cyclohexa

cis-3a-(o-nitrophenyl)octahydroindol-4-one. Building blocks for the synthesis of indole alkaloids

A four-step synthesis of 3a-aryloctahydroindol-4-ones (1) in which the key step is the ozonolysis of 2-allyl-2-(o-nitrophenyl)-1,3-cyclohexanedione (5) followed by reductive aminocyclization was been accomplished. An asymmetric synthesis of the bicyclic s