1380402-75-4Relevant academic research and scientific papers
Dihydropyridones: Catalytic asymmetric synthesis, N- to C-sulfonyl transfer, and derivatizations
Simal, Carmen,Lebl, Tomas,Slawin, Alexandra M. Z.,Smith, Andrew D.
, p. 3653 - 3657 (2012/05/20)
Benzotetramisole (1) promotes the reaction of ammonium enolates derived from arylacetic acids with N-tosyl-α,β-unsaturated ketimines, thus giving dihydropyridones with high diastereo- and enantiocontrol (see scheme). These products readily undergo N- to C-sulfonyl photoisomerization and are derivatized to afford stereodefined piperidines and tetrahydropyrans.
