1380402-82-3Relevant academic research and scientific papers
Asymmetric CONJUGATE ADDITION of MALONATE ESTERS to α,β- UNSATURATED N-sulfonyl imines: An expeditious route to chiral δ-aminoesters and piperidones
Espinosa, Miguel,Blay, Gonzalo,Cardona, Luz,Pedro, José R.
, p. 14861 - 14866 (2013)
The asymmetric conjugate addition of malonate esters to α,β-unsaturated N-sulfonyl imines is catalyzed by PyBOX/La(OTf) 3 complexes in the presence of 4A? MS. The reaction gives the corresponding E enamines bearing a stereogenic center at the allylic position with good yields and enantiomeric ratios up to 97:3. This reaction provides a synthetic entry to chiral δ-aminoesters and piperidones. Copyright
Thermal Ring Expansion of 2-Sulfonylimidoyl-1-phthalimidoaziridines into N-Sulfonylimidazoles
Stukalov, Aleksandr,Suslonov, Vitalii V.,Kuznetsov, Mikhail A.
supporting information, p. 1634 - 1645 (2018/04/24)
The oxidative phthalimidoaziridination of conjugated unsaturated N-sulfonylimines leads, in most cases, to di-substituted, tri-substituted and spiro-fused imidoylaziridines in synthetically useful yields typically above 70 %. The latter are thermally tran
Dihydropyridones: Catalytic asymmetric synthesis, N- to C-sulfonyl transfer, and derivatizations
Simal, Carmen,Lebl, Tomas,Slawin, Alexandra M. Z.,Smith, Andrew D.
supporting information; experimental part, p. 3653 - 3657 (2012/05/20)
Benzotetramisole (1) promotes the reaction of ammonium enolates derived from arylacetic acids with N-tosyl-α,β-unsaturated ketimines, thus giving dihydropyridones with high diastereo- and enantiocontrol (see scheme). These products readily undergo N- to C-sulfonyl photoisomerization and are derivatized to afford stereodefined piperidines and tetrahydropyrans.
