1380422-93-4Relevant academic research and scientific papers
Synthesis, cytotoxic activity and docking studies of new 4-aza-podophyllotoxin derivatives
Hatti, Islavathu,Sreenivasulu, Reddymasu,Jadav, Surender Singh,Jayaprakash, Venkatesan,Kumar, C. Ganesh,Raju, Rudraraju Ramesh
, p. 3305 - 3313 (2015)
The synthesized nine aza-podophyllotoxin derivatives (8a-f, 10, 12 and 14) have been evaluated for their cytotoxicity in a panel of tumor cancer cell lines (Zr-75-1, MCF7, KB, Gurav, DWD, Colo-205, A-549 and Hop62). Among them, 8a and 8b compounds show st
4-AZA-2, 3-DIDEHYDROPODOPHYLLOTOXIN COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF
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Page/Page column 15, (2012/06/30)
The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a- 4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis
