1380424-01-0

Upstream product

• 45774-47-8 5-iodo-1-methyluracil 
• 1380423-88-0 (S)-5-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy)pent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione 
• 1380423-87-9 (S)-2,2,3,3,9,9-hexamethyl-8,8-diphenyl-5-(prop-2-ynyl)-4,7-dioxa-3,8-disiladecane 
• 1380423-86-8 (S)-2,2,3,3,9,9-hexamethyl-8,8-diphenyl-5-(3-(trimethylsilyl)prop-2-ynyl)-4,7-dioxa-3, 8-disiladecane 
• 1380423-85-7 (S)-5-(4,5-dihydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 895153-57-8 (S)-1-(tert-butyldiphenylsilyloxy)-5-(trimethylsilyl)pent-4-yn-2-ol 

Downstream Products

• 1380424-00-9 (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)pent-4-yn-2-yl 2-cyanoethyl diisopropylphosphoramidite 
• 1380424-13-4 C₃₅H₃₄N₂O₉ 

Relevant academic research and scientific papers

Incorporation of an acyclic alkynyl nucleoside analog into siRNA improves silencing activity and nuclease resistance

In order to improve the silencing activity and nuclease resistance of small interfering RNA (siRNA), we designed and synthesized an acyclic thymidine analog containing 4-pentyne-1,2-diol instead of d-ribofuranose. The incorporation of this analog into siR

NUCLEOSIDE ANALOG OR SALT THEREOF, OLIGONUCLEOTIDE ANALOG, GENE EXPRESSION INHIBITOR, AND NUCLEIC-ACID PROBE FOR DETECTING GENE

A nucleoside analog and a salt thereof represented by any of the general formulae (1) to (10) below: wherein R1, R2, and R3 are the same or different groups, and each of the R1, R2 and R3 i