1380424-01-0

Basic information

• Product Name: (S)-5-(5-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-hydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione
• Synonyms: (S)-5-(5-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-hydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 1380424-01-0
• Molecular Weight: 526.589
• Mol File: 1380424-01-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-5-(5-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-hydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-(5-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-hydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione(1380424-01-0)
• EPA Substance Registry System: (S)-5-(5-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-hydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione(1380424-01-0)

Safety Data

• Hazardous Substances Data: 1380424-01-0(Hazardous Substances Data)

Upstream product

• 895153-57-8 (S)-1-(tert-butyldiphenylsilyloxy)-5-(trimethylsilyl)pent-4-yn-2-ol 
• 1380423-85-7 (S)-5-(4,5-dihydroxypent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 1380423-86-8 (S)-2,2,3,3,9,9-hexamethyl-8,8-diphenyl-5-(3-(trimethylsilyl)prop-2-ynyl)-4,7-dioxa-3, 8-disiladecane 
• 1380423-87-9 (S)-2,2,3,3,9,9-hexamethyl-8,8-diphenyl-5-(prop-2-ynyl)-4,7-dioxa-3,8-disiladecane 
• 1380423-88-0 (S)-5-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy)pent-1-ynyl)-1-methylpyrimidine-2,4(1H,3H)-dione 
• 45774-47-8 5-iodo-1-methyluracil 

Downstream Products

• 1380424-00-9 (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)pent-4-yn-2-yl 2-cyanoethyl diisopropylphosphoramidite 
• 1380424-13-4 C₃₅H₃₄N₂O₉ 

Relevant articles and documents

Incorporation of an acyclic alkynyl nucleoside analog into siRNA improves silencing activity and nuclease resistance

In order to improve the silencing activity and nuclease resistance of small interfering RNA (siRNA), we designed and synthesized an acyclic thymidine analog containing 4-pentyne-1,2-diol instead of d-ribofuranose. The incorporation of this analog into siR