1380426-23-2Relevant academic research and scientific papers
Braces for the peptide backbone: Insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations
Tischler, Marco,Nasu, Daichi,Empting, Martin,Schmelz, Stefan,Heinz, Dirk W.,Rottmann, Philipp,Kolmar, Harald,Buntkowsky, Gerd,Tietze, Daniel,Avrutina, Olga
, p. 3708 - 3712 (2012)
Flower power: Potent protease inhibitors containing triazolyl mimics of cis and trans backbone amides were engineered based on the structure of the sunflower trypsin inhibitor 1. The biologically relevant cis-Pro motif was successfully replaced with a non
