1380504-57-3Relevant academic research and scientific papers
Enantioselective Rh-Catalyzed Hydroboration of Silyl Enol Ethers
Dong, Wenke,Lei, Yaqin,Lin, Zhenyang,Ma, Honghui,Xu, Xin,Zhao, Wanxiang
, p. 10902 - 10909 (2021)
The asymmetric hydroboration of alkenes has proven to be among the most powerful methods for the synthesis of chiral boron compounds. This protocol is well suitable for activated alkenes such as vinylarenes and alkenes bearing directing groups. However, the catalytic enantioselective hydroboration of O-substituted alkenes has remained unprecedented. Here we report a Rh-catalyzed enantioselective hydroboration of silyl enol ethers (SEEs) that utilizes two new chiral phosphine ligands we developed. This approach features mild reaction conditions and a broad substrate scope as well as excellent functional group tolerance, and enables highly efficient preparation of synthetically valuable chiral borylethers.
Synthesis of aryl group-modified DIOP dioxides (Ar-DIOPOs) and their application as modular Lewis base catalysts
Ohmaru, Yusuke,Sato, Norimasa,Mizutani, Makoto,Kotani, Shunsuke,Sugiura, Masaharu,Nakajima, Makoto
experimental part, p. 4562 - 4570 (2012/07/17)
Treatment of an optically pure tartaric acid-derived diiodide and various secondary phosphine oxides with LHMDS provides the corresponding aryl group-modified DIOP dioxides (Ar-DIOPOs). The activities of Ar-DIOPOs as Lewis base catalysts were investigated
