1380512-66-2Relevant academic research and scientific papers
A Diels-Alder-based total synthesis of (-)-kainic acid
Orellana, Arturo,Pandey, Sushil K.,Carret, Sebastien,Greene, Andrew E.,Poisson, Jean-Francois
, p. 5286 - 5296 (2012)
An efficient synthesis of (-)-kainic acid, through a high-pressure-promoted Diels-Alder cycloaddition of a vinylogous malonate derived from 4-hydroxyproline, is described. The bicyclic adduct could be converted into the natural product with complete stereocontrol.
