1380572-79-1

Basic information

• Product Name: 1-[5-(tert-butyldimethylsilanyloxymethyl)tetrahydrofuran-2-yl]-3-[((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl]-1H-pyrimidine-2,4-dione
• Synonyms: 1-[5-(tert-butyldimethylsilanyloxymethyl)tetrahydrofuran-2-yl]-3-[((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl]-1H-pyrimidine-2,4-dione
• CAS NO: 1380572-79-1
• Molecular Weight: 724.968
• Mol File: 1380572-79-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[5-(tert-butyldimethylsilanyloxymethyl)tetrahydrofuran-2-yl]-3-[((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl]-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[5-(tert-butyldimethylsilanyloxymethyl)tetrahydrofuran-2-yl]-3-[((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl]-1H-pyrimidine-2,4-dione(1380572-79-1)
• EPA Substance Registry System: 1-[5-(tert-butyldimethylsilanyloxymethyl)tetrahydrofuran-2-yl]-3-[((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl]-1H-pyrimidine-2,4-dione(1380572-79-1)

Safety Data

• Hazardous Substances Data: 1380572-79-1(Hazardous Substances Data)

Upstream product

• 4136-95-2 2,4,6-trichlorobenzoyl chloride 
• 33719-74-3 3,5-dichloroanisole 
• 1380572-64-4 (2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methanone 
• 1380572-78-0 1-[5-(tert-butyldimethylsilanyloxymethyl)-2,5-dihydrofuran-2-yl]-3-[((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl]-1H-pyrimidine-2,4-dione 
• 1380572-77-9 O,O'-((2R,3R,4R,5R)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-(3-(((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl) S,S'-dimethyl dicarbonodithioate 
• 1380572-66-6 (((2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methoxy)methyl) methyl sulfide 

Relevant articles and documents

A new protecting group and linker for uridine ureido nitrogen

(2,6-Dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl) methoxymethyl chloride [1, monomethoxydiph-enylmethoxylmethyl chloroide (MDPM-Cl)] shows a significant relative stability and 1 reacts with uridine ureido nitrogen in the presence of DBU to form the corresponding protected uridine 8 in 95% yield. The MDPM-protected uridines are stable to a wide variety of conditions utilized for the synthesis of analogs of capuramycin and muraymycins. Significantly, the MDPM protecting group can conveniently be deprotected by using 30% TFA in CH 2Cl2. In addition, polymer-bound MDPM-Cl 23 is useful for immobilization of uridine derivatives.