1380596-80-4Relevant academic research and scientific papers
A one-pot, efficient synthesis of polyfunctionalized pyrido[2,3-d] pyrimidines and uncyclized adducts by aldehydes, 1,3-dicarbonyl compounds, and 6-aminouracils
Lu, Guo-Ping,Cai, Chun
, p. 1595 - 1602 (2014)
A one-pot, efficient protocol for the synthesis of polyfunctionalized pyrido[2,3-d]pyrimidines and uncyclized adducts by 6-aminouracils in poly(ethylene glycol) 200/H2O or AcOH was described. An interesting family of pyrido[2,3-d]pyrimidines and uncyclized adducts bearing fused pharmacological active units are prepared. The reaction is free of toxic solvents and catalysts, has simple workup procedure, and has high atom economy, making it more environmentally friendly and suitable for large-scale operations.
Aqua mediated indium(III) chloride catalyzed synthesis of fused pyrimidines and pyrazoles
Khurana, Jitender M.,Chaudhary, Ankita,Nand, Bhaskara,Lumb, Anshika
experimental part, p. 3018 - 3022 (2012/08/08)
The utilization of water as solvent and indium trichloride as promoter for the three-component combinatorial synthesis of a variety of bioactive pyrimidine and pyrazole derivatives (2-10) from aldehydes, 1,3-dicarbonyl compounds, and electron-rich amino h
