1380672-96-7

Basic information

• Product Name: N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride
• Synonyms: N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride
• CAS NO: 1380672-96-7
• Molecular Weight: 349.139
• Mol File: 1380672-96-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride(1380672-96-7)
• EPA Substance Registry System: N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride(1380672-96-7)

Safety Data

• Hazardous Substances Data: 1380672-96-7(Hazardous Substances Data)

Upstream product

• 1380672-78-5 5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2-chloro-phenyl)-amide 
• 1254199-82-0 5-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid methyl ester 
• 30766-12-2 methyl 5-hydroxypicolinate 
• 15069-92-8 5-hydroxypicolinic acid 

Downstream Products

• 1380672-79-6 N'-(2-chlorophenyl)-5-(2,2,2-trifluoro-ethoxy)picolinimidohydrazide 
• 1380672-97-8 4-cyano-benzoic acid N'-(3-{4-(2-chloro-phenyl)-5-[5-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-4H-[1,2,4]triazol-3-yl}-acryloyl)-hydrazide 

Relevant articles and documents

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The present invention relates to compounds of formula (I), to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy: Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway and increased presence of nuclear β-catenin. For example, these may be used in preventing and/or retarding proliferation of tumor cells and metastasis, for example carcinomas such as colon carcinomas.