13807-89-1

Usage

Uses

Used in Perfume Industry:
Ethanol, 2-[(4-methoxyphenyl)methoxy]is used as a solvent for blending and stabilizing various fragrance components in the production of perfumes. Its sweet, aromatic odor enhances the overall scent profile and contributes to the longevity and intensity of the fragrance.
Used in Pharmaceutical Industry:
Anisole is employed as a solvent in the synthesis of various pharmaceutical compounds. Its ability to dissolve a wide range of substances makes it an essential component in the manufacturing process of drugs and medications.
Used in Agrochemical Industry:
Ethanol, 2-[(4-methoxyphenyl)methoxy]is used as a solvent in the formulation of agrochemicals, such as pesticides and herbicides. Its solubility properties allow for the effective delivery of active ingredients to target pests and weeds, improving the overall efficacy of these products.
Used in Food and Beverage Industry:
Anisole is used as a flavoring agent in food and beverages, imparting a unique taste and aroma to various products. Its sweet, aromatic characteristics enhance the flavor profile and contribute to the overall sensory experience of the final product.
Used in Cosmetic Industry:
Ethanol, 2-[(4-methoxyphenyl)methoxy]is used as a fragrance component in cosmetic products, such as perfumes, lotions, and creams. Its sweet, aromatic scent adds a pleasant aroma to these products, making them more appealing to consumers.
Used in Laboratory Applications:
Anisole serves as a versatile solvent in various laboratory processes, including the synthesis of organic compounds, extraction of natural products, and as a mobile phase in chromatographic techniques. Its solubility properties and low toxicity make it a preferred choice for many research and analytical applications.

Upstream product

• 2403-50-1 2-(4-methoxyphenyl)-1,3-dioxolane 
• 128702-34-1 4-[2-(4-Methoxy-benzyloxy)-ethoxymethyl]-phenylamine 
• 2746-25-0 p-Methoxybenzyl bromide 
• 107-21-1 ethylene glycol 
• 824-94-2 p-methoxybenzyl chloride 
• 51759-07-0 (4-methoxybenzyloxy)acetic acid methyl ester 
• 910033-05-5 4-((4-methoxy)benzyloxy)phenylacetic acid methyl ester 
• 104330-36-1 p-methoxybenzyl 3-phenylpropyl ether 
• 105-13-5 4-Methoxybenzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 136057-08-4 C₁₇H₁₉N₃O₃ 
• 137105-30-7 N-{4-[2-(4-Methoxy-benzyloxy)-ethoxymethyl]-phenyl}-2,2-dimethyl-propionamide 
• 128702-31-8 C₁₇H₁₉NO₅ 
• 163400-59-7 2-<(4-Methoxybenzyl)oxy>ethyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 447454-24-2 (p-methoxybenzyloxy)ethyl methanesulfonate 
• 637332-11-7 Acetic acid (2R,3R,4S,5S,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-[2-(4-methoxy-benzyloxy)-ethoxy]-tetrahydro-pyran-3-yl ester 
• 692740-46-8 Acetic acid (2R,3S,4R,5R,6S)-2-{(2S,3R,4S,5S,6S)-5-(acetyl-benzenesulfonyl-amino)-4-benzyloxy-2-benzyloxymethyl-6-[2-(4-methoxy-benzyloxy)-ethoxy]-tetrahydro-pyran-3-yloxy}-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-3-yl ester 
• 910213-00-2 2-(4-methoxybenzyloxy)ethyl diphenylphosphinite 
• 128702-34-1 4-[2-(4-Methoxy-benzyloxy)-ethoxymethyl]-phenylamine 
• 1203447-52-2 1-((3,3-dibromoallyloxy)methyl)-4-methoxybenzene 
• 1203447-53-3 triisopropyl(3-(4-methoxybenzyloxy)prop-1-ynyl)silane 

Relevant academic research and scientific papers

Enzyme-Mediated Directional Transport of a Small-Molecule Walker with Chemically Identical Feet

We describe a small-molecule "walker" that uses enzyme catalysis to discriminate between the relative positions of its "feet" on a track and thereby move with net directionality. The bipedal walker has identical carboxylic acid feet, and "steps" along an isotactic hydroxyl-group-derivatized polyether track by the formation/breakage of ester linkages. Lipase AS catalyzes the selective hydrolysis of the rear foot of macrocyclized walkers (an information ratchet mechanism), the rear foot producing an (R)-stereocenter at its point of attachment to the track. If the hydrolyzed foot reattaches to the track in front of the bound foot it forms an (S)-stereocenter, which is resistant to enzymatic hydrolysis. Only macrocyclic walker-track conjugates are efficiently hydrolyzed by the enzyme, leading to high processivity of the walker movement along the track. Conventional chemical reagents promote formation of the ester bonds between the walker and the track. Iterative macrocyclization and hydrolysis reactions lead to 68% of walkers taking two steps directionally along a three-foothold track.

GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE

The present invention discloses a glycoside compound represented by Formula III, and a preparation method, a composition, use and an intermediate thereof. The glycoside compound provided in the present invention has simple preparation method, can significantly increase the expression of VEGF-A mRNA, and is effective in promoting the angiogenesis. This provides a reliable guarantee for the development of drugs with pro-angiogenic activity for treating cerebral infarction cerebral stroke, myocardial infarction, and ischemic microcirculatory disturbance of lower limbs.

NUCLEOSIDE PRODRUGS AND USES RELATED THERETO

Disclosed are acyclic nucleoside prodrugs with improved metabolic stability and oral bioavailability. In general, the prodrugs are derivatives of acyclic nucleoside phosphonates containing a lipid-like moiety that can increase oral absorption and subsequent stability in the liver and plasma. Preferably, the lipid-like moiety can resist enzyme-mediated ω-oxidation, such as ω -oxidation catalyzed by cytochrome P450 enzymes. Also disclosed are pharmaceutical formulations of the acyclic nucleoside prodrugs. The acyclic nucleoside prodrugs and pharmaceutical formulations thereof can be used to treat viral infections, such as HIV infections, and/or viral-associated cancer, such as HPV-associated cancers.

Iron-catalysed enantioconvergent Suzuki-Miyaura cross-coupling to afford enantioenriched 1,1-diarylalkanes

The first stereoconvergent Suzuki-Miyaura cross-coupling reaction was developed to afford enantioenriched 1,1-diarylalkanes. An iron-based complex containing a chiral cyanobis(oxazoline) ligand framework was best to obtain enantioenriched 1,1-diarylalkanes from cross-coupling reactions between unactivated aryl boronic esters and benzylic chlorides. Enhanced yields were obtained when 1,3,5-trimethoxybenzene was used as an additive, which is hypothesized to extend the lifetime of the iron-based catalyst. Exceptional enantioselectivities were obtained with challenging ortho-substituted benzylic chlorides. This journal is

Compound as well as preparation method and medical application thereof

The invention provides a compound as well as a preparation method and medical application thereof, the compound has a structure as shown in a general formula (I), and can also be a tautomer, a mesomer, a raceme, an enantiomer, a diastereoisomer, or a mixture form thereof, or a pharmaceutically acceptable salt thereof. According to the compound with the structure as shown in the general formula (I)provided by the invention, a specific main chain structure and a corresponding substituent group are selected, so that the obtained compound can be used as an arginase inhibitor, is relatively high in activity, and has a potential treatment prospect in various diseases.

Progress toward the total synthesis of mirabalin isomers

Key fragments of the cytotoxic marine macrolide mirabalin have been synthesized, by using a flexible strategy based on asymmetric reductions to control the hydroxy- and carbamate-bearing stereocenters. In particular, ruthenium or rhodium-mediated asymmetric hydrogenation and transfer hydrogenation were used in combination with a dynamic kinetic resolution to control two contiguous stereocenters in a single step.

A short convergent synthesis of the [3.2.1]dioxabicyclooctane subunit of sorangicin A via regioselective epoxide opening

In this paper, we disclose the synthesis of the dioxabicyclo[3.2.1]octane subunit of the potent antibiotic sorangicin A. The synthesis was achieved in a convergent manner in 8 steps. Regio- and stereoselective intermolecular epoxide opening, ring-closing metathesis and iodo-etherification are key steps. cis-2-Butene diol has been employed as a common staring material.

Organocatalytic Enantioselective 1,3-Difunctionalizations of Morita-Baylis-Hillman Carbonates

The in-situ-generated zwitterionic allylic ylides between Morita-Baylis-Hillman carbonates from isatins and chiral tertiary amine catalysts underwent highly regioselective and enantioselective 1,3-oxo-ethynylation or 1,3-amino-sulfenylation reactions with silyl ethynyl-1,2-benziodoxol-3(1H)-ones or N-(aryl or alkylthio)imides, respectively, giving densely functionalized products bearing a quaternary stereogenic center. An array of diversely structured scaffolds were efficiently constructed from the products, showing the synthetic versatility of the current catalytic strategy.

Chitosan grafted with a heteropolyanion-based ionic liquid as an effective and reusable catalyst for acetalization

Chitosan immobilized with an acidic ionic liquid (CS-VImPS-PW) was fabricated via a radical addition reaction of N-vinylimidazoliumpropane sulfonate and chitosan, followed by acidification with a heteropolyacid. It was characterized by a Fourier transform infrared spectrometer, solid-state 13C nuclear magnetic resonance spectrometer, thermogravimetric analyzer, elemental analyzer, and Hammett indicator. Some acetalization reactions were investigated to evaluate the catalytic activity of CS-VImPS-PW. The results show that CS-VImPS-PW is highly active for the acetalization reactions in high acetal yields ranging from 83.2 to 96.2% and can be reused 8 times without noticeable loss of activity.

Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds with Hypervalent Iodine Reagents

Alkynes have found widespread applications in synthetic chemistry, biology, and materials sciences. In recent years, methods based on electrophilic alkynylation with hypervalent iodine reagents have made acetylene synthesis more flexible and efficient, but they lead to the formation of one equivalent of an iodoarene as side-product. Herein, a more efficient strategy involving a copper-catalyzed oxy-alkynylation of diazo compounds with ethynylbenziodoxol(on)e (EBX) reagents is described, which proceeds with generation of nitrogen gas as the only waste. This reaction is remarkable for its broad scope in both EBX reagents and diazo compounds. In addition, vinyl diazo compounds gave enynes selectively as single geometric isomers. The functional groups introduced during the transformation served as easy handles to access useful building blocks for synthetic and medicinal chemistry.