138100-42-2

Upstream product

• 138100-41-1 5-<(tetrahydropyranyl)oxy>-2-methyl-1-(4-methylphenyl)-1-pentanone 
• 74-88-4 methyl iodide 

Downstream Products

• 138100-43-3 6-<(tetrahydropyranyl)oxy>-3,3-dimethyl-2-(4-methylphenyl)-1-hexene 
• 16982-00-6 1-(1,2,2-trimethylcyclopentyl)-4-methylbenzene 
• 133283-79-1 2,2-dimethyl-1-(4-methylphenyl)-cyclohexane 
• 133283-78-0 4,4-dimethyl-5-(4-methylphenyl)-hex-5-enyl-1-methanesulfonate 
• 138100-45-5 3,3-dimethyl-2-(4-methylphenyl)-1-hexene 
• 138100-44-4 4,4-dimethyl-5-(4-methylphenyl)-5-hexen-1-ol 
• 138100-37-5 3,3-dimethyl-6-iodo-2-(4-methylphenyl)-1-hexene 

Relevant academic research and scientific papers

Construction of a Sterically Congested Carbon Framework via 5-Hexenyllithium Cyclization. Synthesis of (+/-)-Cuparene.

The naturally occuring sesquiterpene (+/-)-cuparene , which contains two contiguous quaternary centers, is produced in good yield by 5-exo-trig cyclization of the 5-hexenyllithium (2) generated from 6-iodo-3,3-dimethyl-2-(4-methylphenyl)-1-hexene (3) by low temperature lithium-iodine exchange.In contrast, radical mediated cyclization of 3 proceeds via the 6-endo-trig mode to give 1,1-dimethyl-2-(4-methylphenyl)cyclohexane.