138102-17-7

Upstream product

• 63202-75-5 ethyl 2-benzoylpent-4-enoate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 4289-20-7 1-phenyl-4-penten-1-yne 
• 1352634-72-0 4-allyl-4-(2-methylallyl)-3-phenyl-4H-isoxazol-5-one 
• 1352634-73-1 3-allyl-5-methyl-2-phenyl-1-azabicyclo[3.1.0]hex-2-ene 
• 1352634-74-2 5-methyl-3-(2-methylallyl)-2-phenylpyrrole 
• 62847-65-8 4-allyl-5-chloro-3-phenyl-isoxazole 

Relevant academic research and scientific papers

Complementing Pyridine-2,6-bis(oxazoline) with Cyclometalated N-Heterocyclic Carbene for Asymmetric Ruthenium Catalysis

A strategy for expanding the utility of chiral pyridine-2,6-bis(oxazoline) (pybox) ligands for asymmetric transition metal catalysis is introduced by adding a bidentate ligand to modulate the electronic properties and asymmetric induction. Specifically, a ruthenium(II) pybox fragment is combined with a cyclometalated N-heterocyclic carbene (NHC) ligand to generate catalysts for enantioselective transition metal nitrenoid chemistry, including ring contraction to chiral 2H-azirines (up to 97 % ee with 2000 TON) and enantioselective C(sp3)?H aminations (up to 97 % ee with 50 TON).