138147-95-2Relevant academic research and scientific papers
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: Synthesis, biological evaluation and 3D-QSAR investigation
Selleri, Silvia,Gratteri, Paola,Costagli, Camilla,Bonaccini, Claudia,Costanzo, Annarella,Melani, Fabrizio,Guerrini, Gabriella,Ciciani, Giovanna,Costa, Barbara,Spinetti, Francesca,Martini, Claudia,Bruni, Fabrizio
, p. 4821 - 4834 (2007/10/03)
The present paper reports the synthesis and binding studies of new 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as selective Peripheral Benzodiazepine Receptor (PBR) ligands. The variability of substituents at the 3-position was investigated and a 3D-
3-amino-5-arylpyrazole-4-acetic acid derivatives exhibiting therapeutic effects
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, (2008/06/13)
This invention provides novel pyrazole-4-acetic acid derivatives which have utility as therapeutic agents which exhibit anxiolytic, anticonvulsant and muscle relaxant effects in warm blooded animals.Illustrative of an invention compound is 3-(dimethylamin
