138148-59-1

Usage

Uses

Used in Pharmaceutical Industry:
Propanoic acid, 3-(methyldithio)is used as an intermediate in the synthesis of Mertansine-13CD3 (M257802), which is the isotope-labelled analog of Mertansine (M257800). Mertansine is a potent cytotoxic agent that plays a crucial role in the development of antibody-drug conjugates (ADCs). These conjugates combine the targeting ability of antibodies with the cytotoxic properties of chemotherapeutic drugs, allowing for a more precise and effective treatment of various cancers.
As an intermediate in the synthesis of Mertansine-13CD3, 3-(methyldithio)propanoic acid contributes to the development of novel ADCs with improved efficacy and reduced side effects. This application highlights the importance of 3-(methyldithio)propanoic acid in advancing cancer treatment options and enhancing patient outcomes.

Downstream Products

• 403518-14-9 3-(methyldisulfanyl)propanoic acid N-hydroxysuccinimide ester 
• 653587-23-6 2'-(triisopropylsilyoxy)-3'-dephenyl-3'-(isobutenyl)-2-debenzoyl-2-(2,5-dimethoxybenzoyl)-7-(methyldisulfanyl-propanoyl)-docetaxel 
• 653586-81-3 C₆₁H₉₅NO₁₆S₂Si₂ 
• 501666-85-9 1-(1S)-(chloromethyl)-5-hydroxy-3-{5-[(5-(3-(acetylthio)propionyl)indol-2-ylcarbonyl)amino]indole-2-carbonyl}-1,2-dihydro-3H-benz[e]indole 
• 741264-78-8 C₆₀H₉₆N₂O₁₅S₂Si₂ 
• 741264-80-2 C₅₈H₉₃NO₁₄S₂Si₂ 
• 653587-21-4 2'-(triisopropylsilyloxy)-3'-dephenyl-3'-(isobutenyl)-7-(methyldisulfanyl-propanoyl)-docetaxel 
• 485801-52-3 3'-dephenyl-3'-(2-methylprop-1-enyl)-7-(3-methyldisulfanylpropanoyl)-10-(morpholine-4-carbonyl)-2'-triisopropylsilyldocetaxel 
• 485801-38-5 3'-dephenyl-3'-(2-methylprop-1-enyl)-10-(3-methyldisulfanylpropanoyl)-7-triethylsilyl-2'-triisopropylsilyldocetaxel 
• 485801-35-2 3'-dephenyl-3'-(2-methylprop-1-enyl)-7-(3-methyldisulfanylpropanoyl)-10-propanoyl-2'-triisopropylsilyldocetaxel