485801-52-3Relevant academic research and scientific papers
Tumor-specific novel taxoid-monoclonal antibody conjugates
Ojima, Iwao,Geng, Xudong,Wu, Xinyuan,Qu, Chuanxing,Borella, Christopher P.,Xie, Hongsheng,Wilhelm, Sharon D.,Leece, Barbara A.,Bartle, Laura M.,Goldmacher, Victor S.,Chari, Ravi V. J.
, p. 5620 - 5623 (2007/10/03)
Taxoids bearing methyldisulfanyl(alkanoyl) groups for taxoid-antibody immunoconjugates were designed, synthesized and their activities evaluated. A highly cytotoxic C-10 methyldisulfanylpropanoyl taxoid was conjugated to monoclonal antibodies recognizing
