1381757-41-0

Basic information

• Product Name: 1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide oxalate
• Synonyms: 1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide oxalate
• CAS NO: 1381757-41-0
• Molecular Weight: 589.608
• Mol File: 1381757-41-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide oxalate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide oxalate(1381757-41-0)
• EPA Substance Registry System: 1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide oxalate(1381757-41-0)

Safety Data

• Hazardous Substances Data: 1381757-41-0(Hazardous Substances Data)

Upstream product

• 211915-84-3 3-[[[2-[[(4-cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionic acid ethyl ester 
• 873-74-5 4-Aminobenzonitrile 
• 42288-26-6 (4-cyanophenyl)glycine 
• 144-62-7 oxalic acid 
• 429658-95-7 3-({2-[(4-carbamimidoylphenylamino)methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}pyridin-2-yl-amino)propionic acid ethyl ester 

Downstream Products

• 211915-06-9 dabigatran etexilate 
• 429658-95-7 3-({2-[(4-carbamimidoylphenylamino)methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}pyridin-2-yl-amino)propionic acid ethyl ester 
• 872728-81-9 N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl] amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-β-alanine ethyl ester methanesulfonate 
• 1381757-44-3 2-(N-(3-ethoxy-3-oxopropyl)-2-((4-(N'-(hexyloxycarbonyl)carbamimidoyl)phenylamino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxamido)pyridine-1-oxide 

Relevant articles and documents

Darbey adds the group ester for an intermediate and its preparation method

The invention discloses a novel intermediate form of dabigatran etexilate, wherein the novel intermediate is a salt of 3-[[[2-[[[4-[[ethyoxyl] formimino]phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-yl]carbonyl](pyridine-2-yl)amino]ethyl propionate as shown in a formula V-A as shown in the specification, and the salt has good purity and stability, can be stored for a long time and can be taken as a process intermediate or a starting raw material for use; and moreover, in the preparation of the subsequent intermediate and the dabigatran etexilate, the reaction operation is simple and convenient, the product purity is high and the industrial application is facilitated.