Oxalic acid was used:
· in the synthesis of hemicellulose hydrolysates of yellow poplars;
· in the synthesis of three-dimensionally ordered macroporous metal oxides or carbonates via templating with polystyrene spheres;
· as supporting electrolyte in the electrochemical synthesis of polyaniline-polypyrrole composite coatings.
Oxalic acid is hygroscopic and sensitive to heat. Oxalic acid may react violently with furfuryl alcohol, silver, sodium, perchlorate, sodium hypochlorite, strong oxidizers, sodium chlorite, acid chlorides, metals and alkali metals. . The heating of mixtures of Oxalic acid and urea has lead to explosions. This is due to the rapid generation of the gases, CO2, CO, and NH3, [Praxis Naturwiss. Chem., 1987, 36(8), 41-42]. Oxalic acid and urea react at high temperatures to form toxic and flammable ammonia and carbon monoxide gasses, and inert CO2 gas [Von Bentzinger, R. et al., Praxis Naturwiss. Chem., 1987, 36(8), 41-42].
1. Oxalic acid can be mainly used as reducing agent and bleaching agent, mordant for dyeing and printing industry, also used in refining rare metal, the synthesis of various oxalate ester amide, oxalate and grass, etc.
2. Used as analytical reagent.
3. Used as laboratory reagents, chromatography analysis reagent, dye intermediates and standard material.
4. Oxalic acid is mainly used for producing drugs such as antibiotics and borneol and solvent for extracting the rare metal, reducing agent and dye, tanning agent, etc. In addition, oxalic acid can also be used for the synthesis of various kinds of oxalate ester, oxalate, and oxamide with diethyl oxalate, sodium oxalate and calcium oxalate having the largest yield. Oxalate can also be used for the production of cobalt-molybdenum-alumina catalyst, cleaning of metal and marble as well as the bleaching of textiles.
An impurity of oxaliplatin which is a coordination complex that is used in cancer chemotherapy.
Oxalic acid is widely distributed in the plant in nature, most existing in the form of oxalic acid salt. C.W. Scheele had for the first time manufactured oxalate in 1776.
Oxalate is the strongest acid among the dicarboxylic acid. Besides having the general properties of the carboxylic acid, it also has reducing property and can quantitatively reduce the seven valence manganese to bivalent manganese. This property is often used for quantitative analysis of potassium permanganate.
5 C2H2O4 + 2 KMnO4 + 3 H2SO4 →K2SO4 + 2 MNSO4 + 8H2O + 10 CO2;
Oxalic acid can also reduce the trivalent iron into bivalent iron. Because of the high solubility of the bivalent iron in the water, we can apply this principle to remove rust on the clothes.
Oxalic acid can react with phosphorus pentachloride to generate phosphorus oxychloride. C2H2O4 + PCl5 → POCl3 + CO + CO2 + 2 HCL.
Oxalic acid can react with many metals to produce oxalic acid salt. In addition to the alkali metal salt and bivalent iron salts with the rest of the oxalic acid salt being poorly soluble in water. Some metal salt, although is poorly soluble in water, can generate complex that is soluble in water.
Fe2 (C2O4) 3 + 3 K2C2O4 + 6 H2O →2 K3 [Fe (C2O4) 3] ? 6 H2O.
Upon heating, alkali metal and alkaline earth metal oxalic acid salt can lose carbon monoxide and form carbonates with carbonate continuing to be subject to heating to be further decomposed into oxide and carbon dioxide. The oxalic acid salt of nickel, cobalt and silver can finally produce metal instead of nonmetal oxide.
The decomposing products of the oxalate are carbon dioxide, carbon monoxide and water.
Oxalate and oxalic acid salt are toxic. Mice, through oral administration, has LD50 of 2000~4000 mg/kg.
The above information is edited by the chemicalbook of Dai Xiongfeng.
As dust or as a solution, can cause severe burns of eyes, skin, or mucous membranes. Ingestion of 5 grams has caused death with symptoms of nausea, shock, collapse, and convulsions coming on rapidly. Repeated or prolonged skin exposure can cause dermatitis and slow-healing ulcers.
ChEBI: An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.
Pre-processing includes chemical reaction with limestone or calcium oxide to generate calcium oxalate. It can be then subject to calcination and can put into particle collection device to collect for reuse.
Upon productive operation, we must wear protective work cloth in order to prevent the skin repeatedly or long-term contact. Wear protective glasses to prevent eye contact. For the nitrogen oxide gas produced during the production process, measures should be taken to absorb before discharge. Work clothes if contaminated, should be replaced every day. Permeable work clothes, if getting wet, should be taken off quickly.
Air & Water Reactions
Water soluble. Hygroscopic
During employment and regular physical examination, we should check the skin, respiratory tract, and kidney function. If there is growing oxalic acid salt crystal in the urine, it is helpful to ascertain the oral poisoning. We should pay attention to follow-up. The determination of blood calcium and blood oxalic acid salt content is also suitable for this purpose.
Oxalic acid is a strong dicarboxylic acid occurring in many plants and vegetables, usually as its calcium or potassium salts. Oxalic acid is the only possible compound in which two carboxyl groups are joined directly; for this reason oxalic acid is one of the strongest organic acids. Unlike other carboxylic acids (except formic acid), it is readily oxidized; this makes it useful as a reducing agent for photography, bleaching, and ink removal. Oxalic acid is usually prepared by heating sodium formate with sodium hydroxide to form sodium oxalate, which is converted to calcium oxalate and treated with sulfuric acid to obtain free oxalic acid.
concentrations of oxalic acid are pretty low in most plants and plant-based foods, but there’s enough in spinach, chard and beet greens to interfere with the absorption of the calcium these plants also contain.
It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.Oxalic acid is a natural acaricide used for treatment against varroa mites in colonies with no/low brood, packages, or swarms. Vaporized oxalic acid is used by some beekeepers as an insecticide against the parasitic Varroa mite.
We should hold it with glass bottle, cask, multi-layer paper bag or metal barrel to prevent mechanical damage. It should be placed in cool, ventilated, dry place for sealed storage. It is best to use the open warehouse and should be placed far away from any places that have potential risk of serious fire. It should be stored separately from antioxidant.
Special Hazards of Combustion Products: Generates poisonous gases
Odorless white solid. Sinks and mixes with water.
This kind of chemical, in case of contact with eyes and skin, should be quickly rinsed with plenty of water; Upon inhaling of large amount, we should immediately move the victim away from the scene to fresh air place; if necessary, apply artificial respiration; if be swallowed, immediately give medical injection with plenty of water for rapid gastric lavage and apply symptomatic treatment.
white crystalline powder