1381762-41-9Relevant academic research and scientific papers
Introduction of histidine units using benzotriazolide activation
Bajaj, Kiran,Panda, Siva S.,Ibrahim, Mohamed A.,El-Feky, Said A.,Katritzky, Alan R.
, p. 110 - 117 (2013/03/29)
Nα-Boc-Nim-(4-toluenesulfonyl-l-histidylbenzotriazole) enables convenient acylation of N-, O-, S-, and C-nucleophiles with no detectable racemization. We report efficient syntheses of novel histidine-containing di-, tri-, and tetra-p
Synthesis and antimalarial bioassay of quinine - peptide conjugates
Panda, Siva S.,Ibrahim, Mohamed A.,Kuecuekbay, Hasan,Meyers, Marvin J.,Sverdrup, Francis M.,El-Feky, Said A.,Katritzky, Alan R.
, p. 361 - 366 (2013/10/08)
Amino acid and peptide conjugates of quinine were synthesized using microwave irradiation in 52-95% yields using benzotriazole methodology. The majority of these conjugates retain in vitro antimalarial activity with IC50 values below 100 nm, similar to quinine.
