1381883-29-9Relevant academic research and scientific papers
Synthesis, biological evaluation and 3D-QSAR studies of novel 4,5-dihydro-1H-pyrazole niacinamide derivatives as BRAF inhibitors
Li, Cui-Yun,Li, Qing-Shan,Yan, Li,Sun, Xiao-Guang,Wei, Ran,Gong, Hai-Bin,Zhu, Hai-Liang
, p. 3746 - 3755 (2012/08/28)
A series of novel 4,5-dihydropyrazole derivatives containing niacinamide moiety as potential V600E mutant BRAF kinase (BRAFV600E) inhibitors were designed and synthesized. Results of the bioassays against BRAF V600E and WM266.4 human
