138194-55-5Relevant academic research and scientific papers
RNase P-Guiding Peptide Conjugates of Oligo(2'-O-methylribonucleotides) as Prospective Antibacterial Agents
Danilin,Koroleva,Novopashina,Venyaminova
, p. 825 - 832 (2019)
Abstract: A novel variant of the synthesis of 3'- and 5'-peptide conjugates of oligo(2'-O-methylribonucleotides) has been developed using thiol-maleimide chemistry. The method is based on the introduction of the maleimide group into an oligonucleotide usi
Facile synthesis of reagents containing a terminal maleimido ligand linked to an active ester
Nielsen,Buchardt
, p. 819 - 821 (2007/10/02)
Condensation of ω-amino acids with maleic anhydride to yield maleamino acids and subsequent esterification with N-hydroxysuccinimide, 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine, or pentafluorophenol to give the corresponding esters in a one pot procedure are described. The reagents can be isolated and purified without chromatography in 7-55% yields.
