1382033-89-7Relevant academic research and scientific papers
Highly enantioselective electrophilic α-bromination of enecarbamates: Chiral phosphoric acid and calcium phosphate salt catalysts
Alix, Aurelien,Lalli, Claudia,Retailleau, Pascal,Masson, Geraldine
supporting information; experimental part, p. 10389 - 10392 (2012/07/28)
Metal-free chiral phosphoric acids and chiral calcium phosphates both catalyze highly enantio- and diastereoselective electrophilic α-bromination of enecarbamates to provide an atom-economical synthesis of enantioenriched vicinal haloamines. Either enantiomer can be formed in good yield with excellent diastereo- and enantioselectivity simply by switching the catalyst from a phosphoric acid to its calcium salt.
