138227-58-4

Upstream product

• 4045-22-1 N-acetyl-4-hydroxypiperidine 
• 100-02-7 4-nitro-phenol 
• 1972-28-7 diethylazodicarboxylate 

Downstream Products

• 138227-59-5 1-acetyl-4-(4-amino-phenoxy)-piperidine 
• 148505-45-7 4-(4-nitrophenoxy)piperidine hydrochloride 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 

Relevant academic research and scientific papers

Piperidinyl and piperazinyl derivatives

Compounds of the formula: STR1 in which R1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2,--CN, 1-imidazolyl or 1,2,4-triazol-1-yl; Y is STR2 --CH2 --, --O--, --S--, or --SO2 --; X is --CH= or --N=; R2 is hydrogen when n is 0, otherwise it is hydrogen or --OH; n is one of the integers 0, 1, 2, 3, 4, 5 or 6; A is STR3 where R3 is alkylsulfonamido of 1 to 6 carbons atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2, --CN, 1-imidazolyl or 1,2,4-triazol-1-yl; or STR4 where R4 is hydrogen or alkyl of 1 to 6 carbon atoms; with the provisos that; a) X is --CH= when Y is STR5 --O-- or --S-- and when Y is STR6 and R2 is --OH; b) X is --N= when A is STR7 c) A is STR8 when Y is --S-- or --SO2 -- and X is --CH=, and their pharmaceutically acceptable salts are Class III antiarrhythmic agents.