1382352-69-3Relevant academic research and scientific papers
Development of CNS multi-receptor ligands: Modification of known D2pharmacophores
Etukala, Jagan R.,Zhu, Xue Y.,Eyunni, Suresh V.K.,Onyameh, Edem K.,Ofori, Edward,Bricker, Barbara A.,Kang, Hye J.,Huang, Xi-Ping,Roth, Bryan L.,Ablordeppey, Seth Y.
, p. 3671 - 3679 (2016)
Several known D2pharmacophores have been explored as templates for identifying ligands with multiple binding affinities at dopamine and serotonin receptors considered as clinically relevant receptors in the treatment of neuropsychiatric disease
Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): A search for new dual-acting agents as potential antidepressants
Zhu, Xue Y.,Etukala, Jagan R.,Eyunni, Suresh V.K.,Setola, Vincent,Roth, Bryan L.,Ablordeppey, Seth Y.
, p. 124 - 132 (2012/08/08)
The synthesis and evaluation of several benzothiazole-based compounds are described in an attempt to identify novel dual-acting 5HT1A receptor and SERT inhibitors as new antidepressants. Binding affinities at the 5HT 1A receptor and
