138271-16-6 Usage
Uses
Used in Pharmaceutical Development:
(Z)-(2,4-difluorophenyl) (4-piperidinyl)methanone, oxime monohydrochloride is used as a reagent for the synthesis of pharmaceutical compounds due to its potential to exhibit biological activity and serve as a ligand for certain receptors or enzymes.
Used in Agrochemical Development:
(Z)-(2,4-difluorophenyl) (4-piperidinyl)methanone, oxime monohydrochloride is used as an intermediate in the development of agrochemicals, contributing to the creation of new products for agricultural applications.
Used in Medicinal Chemistry Research:
(Z)-(2,4-difluorophenyl) (4-piperidinyl)methanone, oxime monohydrochloride is used as a research compound for exploring its potential biological activities and interactions with various receptors or enzymes, which can lead to the discovery of new therapeutic agents.
Used in Organic Synthesis:
(Z)-(2,4-difluorophenyl) (4-piperidinyl)methanone, oxime monohydrochloride is used as a versatile building block in organic synthesis, allowing for the creation of a wide range of chemical products with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 138271-16-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,2,7 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 138271-16:
(8*1)+(7*3)+(6*8)+(5*2)+(4*7)+(3*1)+(2*1)+(1*6)=126
126 % 10 = 6
So 138271-16-6 is a valid CAS Registry Number.
138271-16-6Relevant academic research and scientific papers
Preparation method of palipefidone
-
Paragraph 0062; 0063; 0064; 0065; 0066, (2016/10/10)
The invention provides a preparation method of palipefidone. The preparation method comprises the following steps: dissolving a palipefidone crude product into a heated alcohol solution; adding active carbon under a heating condition; keeping heat and stirring; filtering when the solution is hot to obtain a filtrate; at a temperature of 45 DEG C to 60 DEG C, adding a reducing agent into the filtrate, and keeping the heat and stirring for 30 to 60 minutes; after stirring, controlling to cool for 8 DEG C to 15 DEG C every hour; slowly cooling and crystallizing; after crystallizing, filtering to obtain a solid and a refined mother solution respectively; performing water washing, alcohol washing and vacuum drying on the obtained solid to obtain palipefidone crystallized powder; decompressing and concentrating the refined mother solution and recycling palipefidone secondary precipitate. The preparation method of the palipefidone is simple in process and convenient to operate, does not need special equipment and is suitable for industrial production; a toxin-free or low-toxin solvent is adopted, so that environmental pollution is lowered; the prepared product has high purity, and the content of 9-keto impurities is reduced to be 0.05 percent, even lower.
