138279-32-0 Usage
Uses
Used in Pharmaceutical Industry:
4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid is used as an impurity in Clevidipine (C573700), a calcium channel blocker. The application reason for 4-(2,3-Dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylic acid is that it is a byproduct formed during the synthesis of Clevidipine, which is utilized as an oral antihypertensive agent. The presence of this impurity in Clevidipine is significant as it may affect the drug's efficacy, safety, and overall quality. Therefore, monitoring and controlling the levels of this impurity are crucial in ensuring the therapeutic benefits of Clevidipine as a treatment for hypertension.
Check Digit Verification of cas no
The CAS Registry Mumber 138279-32-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,2,7 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 138279-32:
(8*1)+(7*3)+(6*8)+(5*2)+(4*7)+(3*9)+(2*3)+(1*2)=150
150 % 10 = 0
So 138279-32-0 is a valid CAS Registry Number.
138279-32-0Relevant academic research and scientific papers
PREPARATION OF INTERMEDIATES FOR THE SYNTHESIS OF DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS
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Page/Page column 6, (2011/11/06)
4- (2,3- dichlorophenyl) -1,4- dihydro- 2,6- dimethyl- 5- methoxycarbonyl- 3- pyridinecarboxylic acid, a key intermediate in the synthesis of the cardiovascular calcium channel blocker drug 3-butanoyloxymethoxycarbonyl-5- methoxycarbonyl-4- (2,3-dichlorop
