138296-14-7Relevant academic research and scientific papers
Preparation of protected α-alkoxyglycines
Kawai, Masao,Hosoda, Kouji,Omori, Yoshimasa,Yamada, Keiichi,Hayakawa, Shoko,Yamamura, Hatsuo,Butsugan, Yasuo
, p. 1545 - 1554 (2007/10/03)
N-Carbobenzoxy-α-alkoxyglycine esters were synthesized by H2SO4-catalyzed O-alkylation of N-carbobenzoxy-α-hydroxyglycine and also by base treatment of N-carbobenzoxy-N-chloroglycine methyl ester in the corresponding alcohol. Saponification of the protected α-alkoxyglycines gave free acids which can be used for the synthesis of α-alkoxyglycine residue-containing peptides.
