1383114-63-3

Basic information

• Product Name: 1-(4-(4-iodophenyl)thiazol-2-yl)-2-(pentan-2-ylidene)hydrazine
• Synonyms: 1-(4-(4-iodophenyl)thiazol-2-yl)-2-(pentan-2-ylidene)hydrazine
• CAS NO: 1383114-63-3
• Molecular Weight: 385.272
• Mol File: 1383114-63-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-(4-iodophenyl)thiazol-2-yl)-2-(pentan-2-ylidene)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(4-iodophenyl)thiazol-2-yl)-2-(pentan-2-ylidene)hydrazine(1383114-63-3)
• EPA Substance Registry System: 1-(4-(4-iodophenyl)thiazol-2-yl)-2-(pentan-2-ylidene)hydrazine(1383114-63-3)

Safety Data

• Hazardous Substances Data: 1383114-63-3(Hazardous Substances Data)

Upstream product

• 107-87-9 2-Pentanone 
• 13329-40-3 4-Iodoacetophenone 
• 1752-39-2 propylmethyl ketone thiosemicarbazone 
• 31827-94-8 2-bromo-1-(4-iodophenyl)ethanone 

Relevant articles and documents

Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl)thiazol-2-yl)hydrazine derivatives

Novel (4-(4-iodophenyl)-thiazol-2-yl)hydrazine derivatives were assayed for their in vitro anti-Candida activity, compared to topical and systemic antifungal drugs, against twenty-seven clinical isolates. The presence of aliphatic chains or specific heteroaromatic rings on hydrazone moiety at position C2 and a 4-iodophenyl at C4 of the thiazole ring gave a promising inhibitory activity especially against Candida albicans and Candida krusei. The most active compounds have been also evaluated for their cytotoxicity and in association with clotrimazole for anti-Candida activity.