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Methanesulfonic acid, trifluoro-, 2-cyanophenyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 138313-23-2 Structure
  • Basic information

    1. Product Name: Methanesulfonic acid, trifluoro-, 2-cyanophenyl ester
    2. Synonyms:
    3. CAS NO:138313-23-2
    4. Molecular Formula: C8H4F3NO3S
    5. Molecular Weight: 251.186
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 138313-23-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 2-cyanophenyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 2-cyanophenyl ester(138313-23-2)
    11. EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 2-cyanophenyl ester(138313-23-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 138313-23-2(Hazardous Substances Data)

138313-23-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 138313-23-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,3,1 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 138313-23:
(8*1)+(7*3)+(6*8)+(5*3)+(4*1)+(3*3)+(2*2)+(1*3)=112
112 % 10 = 2
So 138313-23-2 is a valid CAS Registry Number.

138313-23-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-((trifluoromethanesulfonyl)oxy)benzonitrile

1.2 Other means of identification

Product number -
Other names 2-cyanophenyl trifluoromethanesulfonate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138313-23-2 SDS

138313-23-2Relevant articles and documents

2, 3-dihydronaphthalo [2, 3-b] furan-4, 9-diketone compound as well as preparation method and application thereof

-

Paragraph 0138-0140; 0260-0262, (2020/11/05)

The invention provides a 2, 3-dihydronaphthalo [2, 3-b] furan-4, 9-diketone compound as well as a preparation method and application thereof, and belongs to the technical field of medicines. The invention particularly provides the 2, 3-dihydronaphthalo [2, 3-b] furan-4, 9-diketone compounds shown as general formulas I-A and I-B, a pharmaceutical composition containing the compounds, and a preparation method of the compounds. The compound has STAT3 inhibitory activity and can be used for preparing drugs for treating and/or preventing diseases related to STAT3 activity, and the diseases comprisevarious cancers such as breast cancer, lung cancer, oral cancer, kidney cancer, esophageal cancer, liver cancer, stomach cancer, intestinal cancer, cervical cancer and ovarian cancer.

Achieving vinylic selectivity in Mizoroki-heck reaction of cyclic olefins

Wu, Xiaojin,Lu, Yunpeng,Hirao, Hajime,Zhou, Jianrong

supporting information, p. 6014 - 6020 (2013/06/26)

In Heck reactions of cyclic olefins, the products usually have aryl groups that end up at the allylic and/or homoallylic position. We herein report new selectivity that adds aryl groups to the vinylic position. Cyclic olefins of various ring size worked well. The desired isomers were produced by palladium-hydride-catalyzed isomerization of the initial products. Thus, a specific catalyst must be used so that it can perform two jobs under one set of reaction conditions. Copyright

CHIRAL PHOSPHINES FOR PALLADIUM-CATALYZED ASYMMETRIC ALPHA-ARYLATION OF ESTER ENOLATES TO PRODUCE TERTIARY STEREOCENTERS IN HIGH ENANTIOSELECTIVITY

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Paragraph 00162-00163, (2013/03/26)

The disclosure provides new and improved methods for the Pd-catalyzed asymmetric α-arylation of ester compounds, which produce the corresponding α-aryl moiety in high enantioselectivity (generally >90% ee). The present methods utilize a palladium catalyst supported by new (R)-H8-BINOL-derived monophosphine ligands. The method is applicable to a wide variety of aryl triflate substrates having variations in both electronic and steric properties. These aryl triflate substrates react with various α-alkyl (Z)- and/or (E)-0-trimethylsilyl ketene acetals in the presence of a Pd catalyst, (R)-H8-BINOL-derived monophosphine ligand, and a mild activator, for example, LiOAC, to provide the asymmetric α-arylation of ester compounds in high ee.

Intermolecular mizoroki-heck reaction of aliphatic olefins with high selectivity for substitution at the internal position

Qin, Liena,Ren, Xinfeng,Lu, Yunpeng,Li, Yongxin,Zhou, Jianrong

supporting information; experimental part, p. 5915 - 5919 (2012/07/30)

New ligand for old reaction: The title reaction of aryltriflates with aliphatic olefins leads to substitution at the internal position with high selectivity. The ratio of the desired isomer (shown in the scheme) to the sum of all other isomers is generall

Palladium-catalyzed desulfitative arylation by C-O bond cleavage of aryl triflates with sodium arylsulfinates

Zhou, Chao,Liu, Qingjiang,Li, Yaming,Zhang, Rong,Fu, Xinmei,Duan, Chunying

, p. 10468 - 10472 (2013/01/15)

An efficient Pd-catalyzed desulfitative coupling reaction of sodium arylsulfinates as arylation reagents by C-O bond cleavage of aryl triflates was developed. With only 2 mol % of Pd(OAc)2 as catalyst and XPhos as ligand, the reaction proceeded well for a range of substrates.

An enantioselective, intermolecular α-arylation of ester enolates to form tertiary stereocenters

Huang, Zhiyan,Liu, Zheng,Zhou, Jianrong

supporting information; experimental part, p. 15882 - 15885 (2011/11/13)

In transition-metal catalyzed, asymmetric α-arylation of carbonyl compounds, formation of tertiary centers with high enantioselectivity is a longstanding problem, due to easy enolization of the monoarylation products. Herein, we report such examples using a palladium catalyst supported by a new, (R)-H8-BINOL-derived monophosphine. Silyl ketene acetals, together with a weakly basic activator, were used as equivalents of ester anions, and they reacted smoothly with aryl triflates in excellent enantiomeric excess (ee). The usefulness of the reaction was demonstrated in a gram-scale synthesis of (S)-Naproxen in 92% ee.

One-pot synthetic procedure for 2,2′-disubstituted biaryls via the Suzuki coupling reaction of aryl triflates in a biphasic solvent system

Miura, Masanori,Koike, Takanori,Ishihara, Tsukasa,Hirayama, Fukushi,Sakamoto, Shuichi,Okada, Minoru,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi

, p. 3809 - 3820 (2007/10/03)

A one-pot synthetic procedure for 2,2′-disubstituted biaryls was developed via a Suzuki cross-coupling reaction of aryl triflates in a biphasic solvent system. The effects of various bases and solvents were investigated. Results showed that the Na2/

Preparation and Palladium-Catalyzed Cross-Coupling of Aryl Triethylammonium Bis(catechol) Silicates with Aryl Triflates

Seganish, W. Michael,DeShong, Philip

, p. 1137 - 1143 (2007/10/03)

Pentavalent aryl and heteroaryl bis(catechol) silicates undergo palladium-catalyzed cross-coupling with aryl and heteroaryl triflates in the presence of a fluoride source in excellent yields. These solid, air-stable bis(catechol) silicates are prepared from a high-yielding displacement reaction between catechol and an aryl siloxane in the presence of an amine base. The cross-coupling reaction is tolerant of a wide range of electron-donating and electron-withdrawing groups. Several examples of di-ortho-substituted triflates are successfully coupled with these reagents.

A facile route to aryl amines: Nucleophilic substitution of aryl triflates

Schio, Laurent,Lemoine, Guy,Klich, Michel

, p. 1559 - 1562 (2007/10/03)

The aromatic nucleophilic substitution (S(N)Ar) between aryl triflates and secondary amines has been studied. In the absence of solvent, the reaction proceeds at room temperature for nitro and cyano activated aryl triflates and requires higher temperatures in the case of carboxy activation. Variable triflate reactivity could be explained in terms of frontier molecular orbital theory. This methodology has been applied for the synthesis of substituted piperidyl pyridines.

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