138313-59-4Relevant academic research and scientific papers
A Simple Method for the Preparation of Stainless and Highly Pure Trichloroacetimidates
Ikeuchi, Kazutada,Murasawa, Kentaro,Yamada, Hidetoshi
, p. 1308 - 1312 (2019)
We describe a method for obtaining various allylic, benzylic, and glucosyl 2,2,2-trichloroacetimidates (TCAIs) as stainless liquids or solids at the crude stage. The general synthetic method for the preparation of TCAIs often leads to stained products, and further purification of crude TCAIs causes decomposition due to their instability. In the described method, we use a solvent that barely dissolves the reactant, providing stainless and sufficiently pure TCAIs without requiring a purification step. Furthermore, the reaction mixture is turbid at the beginning and clear at the end, allowing us to monitor the progress of the reaction visually.
Rhodium-catalyzed regio- and enantioselective amination of racemic secondary allylic trichloroacetimidates with N-methyl anilines
Arnold, Jeffrey S.,Cizio, Gregory T.,Heitz, Drew R.,Nguyen, Hien M.
supporting information, p. 11531 - 11533,3 (2012/12/12)
We report the chiral diene ligated rhodium-catalyzed dynamic kinetic asymmetric transformation (DYKAT) of racemic secondary allylic trichloroacetimidates with a variety of N-methyl anilines, providing allylic N-methyl arylamines in high yields, regioselec
Rhodium-catalyzed regio- and enantioselective amination of racemic secondary allylic trichloroacetimidates with N-methyl anilines
Arnold, Jeffrey S.,Cizio, Gregory T.,Heitz, Drew R.,Nguyen, Hien M.
supporting information, p. 11531 - 11533 (2013/01/15)
We report the chiral diene ligated rhodium-catalyzed dynamic kinetic asymmetric transformation (DYKAT) of racemic secondary allylic trichloroacetimidates with a variety of N-methyl anilines, providing allylic N-methyl arylamines in high yields, regioselec
Rhodium-catalyzed regioselective amination of secondary allylic trichloroacetimidates with unactivated aromatic amines
Arnold, Jeffrey S.,Stone, Robert F.,Nguyen, Hien M.
supporting information; experimental part, p. 4580 - 4583 (2010/12/24)
The use of unactivated aromatic amines in the rhodium-catalyzed regioselective amination of secondary allylic trichloroacetimidates is explored. The desired N-arylamines are obtained in high yields and regioselectivity, favoring the branched amination pro
