1383439-54-0

Basic information

• Product Name: C₂₀H₁₉NO₃
• CAS NO: 1383439-54-0
• Molecular Weight: 321.376
• Mol File: 1383439-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₉NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₉NO₃(1383439-54-0)
• EPA Substance Registry System: C₂₀H₁₉NO₃(1383439-54-0)

Safety Data

• Hazardous Substances Data: 1383439-54-0(Hazardous Substances Data)

Upstream product

• 31636-92-7 4-carbonylpentyl benzoate 
• 1071-73-4 5-Hydroxy-2-pentanone 
• 1352086-01-1 3-amine-4-carbonylpentyl benzoate 
• 1352085-99-4 3-azido-4-carbonylpentyl benzoate 
• 874-60-2 4-methyl-benzoyl chloride 
• 1352085-98-3 3-bromo-4-carbonylpentyl benzoate 

Downstream Products

• 477541-32-5 methanesulfonic acid 2-(5-methyl-2-p-tolyloxazol-4-yl)ethyl ester 
• 1383439-81-3 C₂₅H₂₉NO₄ 
• 1352085-91-6 3-{2-ethyl-4-[2-(5-methyl-2-p-tolyloxazol-4-yl)ethoxy]phenyl}propanoic acid 
• 157169-71-6 2-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]ethanol 

Relevant articles and documents

Design and synthesis of 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)- 5-methyloxazol-4-yl]ethoxy}phenyl)propanoic acid: A novel triple-acting PPARα, -γ, and -δ Agonist

The design and synthesis of triple-acting PPARα, -γ, and -δ agonist 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]- ethoxy}phenyl)propanoic acid (1a) is described. The compound possesses a potent triple-acting PPARα, -γ, and -δ agonist profile with an EC50 of 0.029, 0.013, and 0.029 μM, respectively. The synthetic route, involving the synthesis of oxazole rings as the key step, starts from commercially available 3-oxopentanoic acid methyl ester and 3- hydroxyacetophenone to afford the target compound 1 with an overall yield of 32%.