1383475-71-5Relevant academic research and scientific papers
Catalytic asymmetric synthesis of α,β-disubstituted α,γ-diaminophosphonic acid precursors by michael addition of α-substituted nitrophosphonates to nitroolefins
Tripathi, Chandra Bhushan,Kayal, Satavisha,Mukherjee, Santanu
, p. 3296 - 3299 (2012/08/08)
Michael additions of α-substituted nitrophosphonates to various nitroolefins are shown to proceed with high diastereo- and enantioselectivity when catalyzed by a quinine-derived thiourea-tertiary amine bifunctional catalyst and generate α,γ-diaminophosphonic acid precursors with contiguous quaternary and tertiary stereocenters.
