919-19-7

Basic information

• Product Name: ACETYLPHOSPHONIC ACID DIETHYL ESTER
• Synonyms: DIETHYL ACETYLPHOSPHONATE;ACETYLPHOSPHONIC ACID DIETHYL ESTER;1-Oxoethylphosphonic acid diethyl ester
• CAS NO: 919-19-7
• Molecular Formula: C₆H₁₃O₄P
• Molecular Weight: 180.14
• Mol File: 919-19-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 54-55°C 0,5mm
• Flash Point: 95.6°C
• Appearance: /
• Density: 1,11 g/cm3
• Refractive Index: 1.4210-1.4240
• CAS DataBase Reference: ACETYLPHOSPHONIC ACID DIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: ACETYLPHOSPHONIC ACID DIETHYL ESTER(919-19-7)
• EPA Substance Registry System: ACETYLPHOSPHONIC ACID DIETHYL ESTER(919-19-7)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 919-19-7(Hazardous Substances Data)

Usage

General Description

Acetylphosphonic acid diethyl ester is a chemical compound with the molecular formula C6H15O4P. It is a colorless, flammable liquid that is often used as an intermediate in the synthesis of various organic compounds. ACETYLPHOSPHONIC ACID DIETHYL ESTER is known to have herbicidal properties and is used in some commercial herbicide formulations. Acetylphosphonic acid diethyl ester is also used as a chemical intermediate in pharmaceutical and agrochemical production. It is important to handle this compound with care, as it can be harmful if swallowed, inhaled, or comes into contact with the skin.

Upstream product

• 64-19-7 acetic acid 
• 122-52-1 triethyl phosphite 
• 3266-66-8 acetyl diethyl phosphite 
• 506-96-7 Acetyl bromide 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 14540-22-8 diethyl (tert-butyl) phosphite 
• 75-36-5 acetyl chloride 
• 22752-34-7 diethyl 1-methyl-3-oxo-1-butenylphosphonate 
• 65600-72-8 ethyl P-(diethoxymethyl)phosphonite 

Downstream Products

• 1602490-22-1 diethyl (1S)-1-hydroxy-1-[(2R)-5-oxo-2,5-dihydrofuran-2-yl]ethylphosphonate 
• 762-04-9 phosphonic acid diethyl ester 
• 76782-77-9 Diethyl-(1-methyl-3-phenyl-1,2-propadienyl)phosphat 
• 54788-35-1 diethyl 1-aminoethylphosphonate 
• 15336-73-9 diethyl 1-hydroxyethylphosphonate 
• 19239-48-6 1-Cyanethyldiethylphosphat 
• 64244-31-1 3-(diethoxyphosphinoyl)-1-phenyl-2-azabut-1-ene 

Relevant articles and documents

Acyloxy derivatives of trivalent phosphorus in amidoalkylation of hydrophosphoryl compounds

In order to model the previously suggested mechanism of the P-C bond formation via the Arbuzov reaction, we have studied the interaction of diethylacylphosphite (prepared beforehand as well as generated in situ from tetraethylpyrophosphite) with the in situ generated acyliminium cation. Various conditions of in situ generation of acylphosphite derivatives of P(III) from hydrophosphoryl compounds and acyliminium ions from N,N′- alkylidenebiscarbamates have been investigated: solvent nature, acid catalyst, and the reagents mixing order). The results obtained have confirmed the suggested mechanism of three-component reaction of amidoalkylation of hydrophosphoryl compounds with the formation of P-C bond via the Arbuzov reaction of in situ formed intermediates.

tert-BUTYL PHOSPHITES. SYNTHESIS AND PROPERTIES

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Reactions of mixed esters of phosphorus(III) acids, containing simultaneously alkoxy and triorganosiloxy groups, with halogens, alkyl halides, and acyl halides

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