138351-00-5Relevant articles and documents
Heteroatom-directed lateral lithiation: Synthesis of isoquinoline derivatives from N-(tert-butoxycarbonyl)-2-methylbenzylamines
Clark,Jahangir,Langston
, p. 23 - 30 (2007/10/02)
Methodology for the preparation of isoquinoline derivatives from N-(tert-butoxycarbonyl)-2-methylbenzylamines (1) was developed. Conversion of 1 to the dilithio species followed by condensation with DMF afforded Boc-3-hydroxy-1,2,3,4-tetrahydroisoquinolin