1383533-41-2Relevant academic research and scientific papers
Approach to highly functionalized oxazolones by a Pd-catalyzed cyclization of N-alkynyl tert-butyloxycarbamates
Lu, Zenghui,Xu, Xiaowei,Yang, Zhaozhen,Kong, Lichun,Zhu, Gangguo
, p. 3433 - 3436 (2012)
A mild and operationally simple approach to highly functionalized oxazolones has been developed, which involves an intramolecular oxypalladation of N-alkynyl tert-butyloxycarbamates, followed by either protonolysis of the alkenyl C-Pd bond to afford 3,5-disubstituted oxazolones or allylation with allyl halides in the presence of Ag2CO3 to generate 3,4,5-trisubstituted oxazolones, respectively.
