1383533-48-9Relevant academic research and scientific papers
Metal-free hydration of ynamides: Convenient approach to amides
Huang, Hai,Tang, Luning,Xi, Yang,He, Guangke,Zhu, Hongjun
, p. 1873 - 1876 (2016)
The trifluoroacetic acid (TFA) mediated hydration of ynamides was developed, which is an efficient approach for the synthesis of N-monosubstituted amides. This convenient method is effective with a wide range of substrates under room temperature condition, and the products are obtained in high to excellent yields through an easy work-up process.
