1383543-85-8Relevant articles and documents
Strategy for catch and release of azide-tagged biomolecules utilizing a photolabile strained alkyne construct
Golkowski, Martin,Pergola, Carlo,Werz, Oliver,Ziegler, Thomas
, p. 4496 - 4499 (2012/08/07)
A photolabile o-nitrobenzyl linker-cyclooctyne conjugate was prepared, immobilized on poly(methacrylate) beads and utilized as a trap for azide-functionalized compounds. These could be released by 365 nm UV light irradiation in high yield and purity. The reagent-free and time economic catch and release protocol was deemed useful for chemical proteomics applications.