1393183-02-2

Upstream product

• 462100-06-7 2-[2-[2-(2-[[(tert-butoxy)carbonyl]amino]ethoxy)ethoxy]ethoxyl]acetic acid 
• 162827-96-5 methyl 4-(2-methoxy-5-nitro-4-(1-trifluoroacetamido-ethyl)phenoxy)butanoate 
• 1383543-84-7 4-{4-[14-(tert-butoxycarbonyl)amino-4-oxo-6,9,12-trioxa-3-azatetradec-2-yl]-2-methoxy-5-nitrophenoxy}butanoic acid methyl ester 
• 1383543-83-6 4-[2-methoxy-5-nitro-4-(1-aminoethyl)phenoxy]butanoic acid methyl ester hydrochloride 
• 1383543-85-8 4-{4-[14-(11,12-didehydro-5,6-dihydrodibenzo[a,e]cycloocten-5-oxycarbonylamino)-4-oxo-6,9,12-trioxa-3-azatetradec-2-yl]-2-methoxy-5-nitrophenoxy}butanoic acid methyl ester 
• 100-02-7 4-nitro-phenol 
• 1146195-73-4 methyl 2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-oate 
• 1027338-09-5 11,12-didehydro-5,6-dihydrodibenzo[a,e]cycloocten-5-yl carbonic acid 4-nitrophenyl ester 

Relevant academic research and scientific papers

Strategy for catch and release of azide-tagged biomolecules utilizing a photolabile strained alkyne construct

A photolabile o-nitrobenzyl linker-cyclooctyne conjugate was prepared, immobilized on poly(methacrylate) beads and utilized as a trap for azide-functionalized compounds. These could be released by 365 nm UV light irradiation in high yield and purity. The reagent-free and time economic catch and release protocol was deemed useful for chemical proteomics applications.