138356-07-7Relevant academic research and scientific papers
Stereoselective Synthesis of 1,3-Amino Alcohols and 1,3-Amino Ketones
Barluenga, Jose,Aguilar, Enrique,Fustero, Santos,Olano, Bernardo,Viado, Argimiro L.
, p. 1219 - 1223 (2007/10/02)
syn,anti-N-Alkyl-1,3-amino alcohols 2 with three chiral centers are synthesized with high stereoselectivity by reduction of the corresponding anti-N-acylamino ketones 1 with LiAlH4/TiCl4.The intermediate N-acylamino alcohols 3 can be isolated when DIBALH/
