1383579-39-2

Basic information

• Product Name: N-(4-acetylphenyl)-N-({4-amino-2-(methylthio)furo[2,3-d]pyrimidin-5-yl}methyl)methanesulfonamide
• Synonyms: N-(4-acetylphenyl)-N-({4-amino-2-(methylthio)furo[2,3-d]pyrimidin-5-yl}methyl)methanesulfonamide
• CAS NO: 1383579-39-2
• Molecular Weight: 406.486
• Mol File: 1383579-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-acetylphenyl)-N-({4-amino-2-(methylthio)furo[2,3-d]pyrimidin-5-yl}methyl)methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-acetylphenyl)-N-({4-amino-2-(methylthio)furo[2,3-d]pyrimidin-5-yl}methyl)methanesulfonamide(1383579-39-2)
• EPA Substance Registry System: N-(4-acetylphenyl)-N-({4-amino-2-(methylthio)furo[2,3-d]pyrimidin-5-yl}methyl)methanesulfonamide(1383579-39-2)

Safety Data

• Hazardous Substances Data: 1383579-39-2(Hazardous Substances Data)

Upstream product

• 99-92-3 p-aminobenzophenone 
• 5317-89-5 4'-(methylsulfonylamino)acetophenone 
• 1383579-32-5 4-amino-5-(hydroxymethyl)-2-(methylthio)furo[2,3-d]pyrimidine 
• 1198054-16-8 ethyl 4-amino-2-(methylthio)furo[2,3-d]pyrimidine-5-carboxylate 

Relevant articles and documents

4-Amino-5-(arylaminomethyl)-2-(methylthio)furo[2,3-d]pyrimidines via Mitsunobu reaction of 4-amino-5-(hydroxymethyl)-2-(methylthio)furo[2,3-d] pyrimidine with N-mesyl- and N-nosylarylamines

An efficient method for the synthesis of 4-amino-5-(arylaminomethyl)-2- (methylthio)furo[2,3-d]pyrimidines via the Mitsunobu reaction of 4-amino-5-(hydroxymethyl)-2-(methylthio)furo[2,3-d]pyrimidine with N-mesyl- and N-nosylarylamines, and subsequent removal of the mesyl and nosyl groups, has been developed. The influence of substituents in the arylamine moiety on the Mitsunobu reaction was investigated. An unexpected nucleophilic substitution of a nitro group in the reaction of N-({4-amino-2-(methylsulfonyl)furo[2,3-d] pyrimidin-5-yl}methyl)-4-nitro-N-phenylbenzenesulfonamide with sodium methoxide was observed. Georg Thieme Verlag Stuttgart · New York.