1383709-12-3

Basic information

• Product Name: ((S)-1-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester
• Synonyms: ((S)-1-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester
• CAS NO: 1383709-12-3
• Molecular Weight: 528.583
• Mol File: 1383709-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((S)-1-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((S)-1-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester(1383709-12-3)
• EPA Substance Registry System: ((S)-1-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester(1383709-12-3)

Safety Data

• Hazardous Substances Data: 1383709-12-3(Hazardous Substances Data)

Upstream product

• 1383709-50-9 6-(4-(4-fluorophenoxy)phenyl)pyridin-2-amine 
• 117142-26-4 (S)-2-tert-butoxycarbonylamino-3-pyridin-3-yl-propionic acid 
• 19798-81-3 2-Amino-6-bromopyridine 
• 1355052-34-4 2-(4-(4-fluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 1383709-73-6 (S)-2-amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-yl}-3-pyridin-3-yl-propionamide hydrochloride 
• 1383709-14-5 (S)-2-acetylamino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-yl}-3-pyridin-3-yl-propionamide 

Relevant articles and documents

SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS

The invention relates to substituted pyridine compounds of Formula I: (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, R1b, R2a, R2b, R2c, A1, A2, and X are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.