1383709-50-9

Upstream product

• 19798-81-3 2-Amino-6-bromopyridine 
• 1355052-34-4 2-(4-(4-fluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 1383709-68-9 C₂₇H₃₀FN₃O₃ 
• 1383709-12-3 ((S)-1-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester 
• 1383709-43-0 (E)-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-2-phenylethenesulfonamide 
• 1383708-62-0 (S)-2-acetamido-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-3-phenylpropanamide 
• 1383709-51-0 C₂₈H₃₂FN₃O₄ 
• 1383708-61-9 (S)2-acetamido-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-4-methylpentanamide 
• 1383709-71-4 C₂₅H₂₆FN₃O₃ 
• 1383708-92-6 2-(4-((6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)amino)piperidin-1-yl)acetic acid 
• 1383709-73-6 (S)-2-amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-yl}-3-pyridin-3-yl-propionamide hydrochloride 
• 1383709-14-5 (S)-2-acetylamino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pyridin-2-yl}-3-pyridin-3-yl-propionamide 
• 1383709-53-2 C₂HF₃O₂*C₂₃H₂₄FN₃O₂ 
• 1383708-63-1 (S)-N-(1-((6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)amino)-4-methyl-1-oxopentan-2-yl)picolinamide 
• 1383708-69-7 (S)-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-2-(3-isopropylureido)-4-methylpentanamide 
• 1383709-70-3 C₂HF₃O₂*C₂₂H₂₂FN₃O 

Relevant academic research and scientific papers

SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS

The invention relates to substituted pyridine compounds of Formula I: (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, R1b, R2a, R2b, R2c, A1, A2, and X are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.