138371-99-0

Upstream product

• 931-33-9 4-bromopyrrole-2-carboxaldehyde 
• 98-09-9 benzenesulfonyl chloride 
• 617-84-5 N-formyldiethylamine 
• 1192217-75-6 1-(benzenesulfonyl)-3-bromo-1H-pyrrole 
• 68-12-2 N,N-dimethyl-formamide 
• 1229516-64-6 N-benzenesulfonyl-2,4-dibromopyrrole 
• 109-94-4 formic acid ethyl ester 
• 1246187-73-4 N-benzenesulfonyl-2,5-dibromopyrrole 
• 16851-82-4 N-phenylsulfonylpyrrole 

Downstream Products

• 138372-00-6 4-Bromo-2-(1,3-dioxolan-2-yl)-1-(phenylsulfonyl)pyrrole 
• 138372-01-7 1-Benzenesulfonyl-2-[1,3]dioxolan-2-yl-1H-pyrrole 
• 138372-03-9 (R)-1-(1-Benzenesulfonyl-5-[1,3]dioxolan-2-yl-1H-pyrrol-3-yl)-5,5-dimethyl-dihydro-oxazolo[3,4-c]oxazol-3-one 
• 138372-02-8 (R)-4-[(1-Benzenesulfonyl-5-[1,3]dioxolan-2-yl-1H-pyrrol-3-yl)-chloro-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 138372-16-4 t-Butyl (R)-4-<5-(1,3-dioxolan-2-yl)-1-(phenylsulfonyl)pyrrol-3-yl>hydroxymethyl-2,2-dimethyl-3-oxazolidinecarboxylate 
• 138372-05-1 t-Butyl (R)-4-<5-formyl-1-(phenylsulfonyl)pyrrol-3-yl>acetoxymethyl-2,2-dimethyl-3-oxazolidinecarboxylate 
• 138372-17-5 (S)-4-[(1-Benzenesulfonyl-5-[1,3]dioxolan-2-yl-1H-pyrrol-2-yl)-hydroxy-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 138372-04-0 t-Butyl (R)-4-<5-(1,3-Dioxolan-2-yl)-1-(phenylsulfonyl)pyrrol-3-yl>acetoxymethyl-2,2-dimethyl-3-oxazolidinecarboxylate 
• 138417-55-7 t-Butyl (R,S)-N-<4-<4-(3-t-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)acetoxymethyl-1-(phenylsulfonyl)pyrrol-2-yl>-4-oxobutanoyl>-N-methylvalinate 
• 138395-25-2 (R)-4-[Acetoxy-(1-benzenesulfonyl-5-{3-[((S)-1-tert-butoxycarbonyl-2-methyl-propyl)-methyl-carbamoyl]-propynoyl}-1H-pyrrol-3-yl)-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 138395-24-1 t-Butyl (R,S)-N-<4-<4-(3-t-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)acetoxymethyl-1-(phenylsulfonyl)pyrrol-2-yl>-4-hydroxy-2-butynoyl>-N-methylvalinate 

Relevant academic research and scientific papers

Preparation method of pyrrole derivative and intermediate thereof

The invention discloses a preparation method of a pyrrole derivative and an intermediate thereof. , 2, 4 -dichlorophenol and 4 -bromo - 1H - pyrrole -2 - formaldehyde which are wide in source are used as raw materials and are substituted. The target compo

Optional synthesis of 2- OR 5-substituted 3-bromopyrroles via bromine-lithium exchange of N-benzenesulfonyl-2,4-dibromopyrrole

The regioselective bromine-lithium exchange of N-benzenesulfonyl-2,4- dibromopyrrole (6) with n-BuLi followed by treatment with various electrophiles gave 5-substituted 3-bromopyrroles (5) in excellent yields. In contrast, the sequential treatment of 6 wi

Directed lithiation of N -benzenesulfonyl-3-bromopyrrole. Electrophile-controlled regioselective functionalization via dynamic equilibrium between C-2 and C-5 lithio species

(Figure presented) Directed lithiation of N-benzenesulfonyl-3-bromopyrrole (1) with LDA in THF at -78 °C generated C-2 lithio species 3 selectively. Reactions of 3 with reactive electrophiles produced the corresponding 2-functionalized pyrroles 4. On the

Ethyl α-amino-β,β-diethoxypropionate, a useful synthon for the preparation of 3,4-fused pyridine-6-carboxylates from aromatic aldehydes

An efficient synthesis of ethyl α-amino-β,β-diethoxypropionate (1), via a titanium tetrachloride-catalyzed coupling reaction of ethyl nitroacetate and triethyl orthoformate, is described. Condensation of 1 with various aldehydes followed by reduction and

The Second Generation Synthesis of a Tumor Promoter Pendolmycin

Total synthesis of a tumor promoter pendolmycin (1) was accomplished in the stereospecific manner using a D-serine derivative 7 and an L-valine derivative 16 as chiral sources.Methyl 2-(bromomethyl)benzoate was used for the critical step of the indole cyc