1383735-30-5

Upstream product

• 1150617-54-1 6-bromo-1H-pyrazolo[4,3-b]pyridine 
• 541-41-3 chloroformic acid ethyl ester 
• 1383735-65-6 1-{6-bromo-1H-pyrazolo[4,3-b]pyridin-1-yl}ethan-1-one 
• 67443-38-3 5-bromo-2-chloro-3-nitropyridine 
• 1301214-71-0 N-(5-bromo-2-methyl-pyridin-3-yl)-acetamide 
• 914358-73-9 5-bromo-2-methylpyridin-3-ylamine 
• 911434-05-4 5-bromo-2-methyl-3-nitropyridine 
• 911434-04-3 2-(5-bromo-3-nitro-pyridin-2-yl)-malonic acid diethyl ester 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 

Downstream Products

• 1383735-31-6 C₁₅H₁₂FN₃O₂ 
• 1383735-64-5 C₁₅H₁₆FN₃O₂ 
• 1383735-67-8 C₁₃H₁₀FN₃ 
• 1383735-34-9 C₁₆H₁₅ClFN₃O₃ 
• 1383733-69-4 1-(4-fluorophenyl)-4-[(S)-1-(2-methanesulfonyl-pyridin-4-yl)-butylcarbamoyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-6-carboxylic acid ethyl ester 
• 1383733-70-7 1-(4-fluorophenyl)-4-[(S)-1-(2-methanesulfonyl-pyridin-4-yl)-butylcarbamoyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-6-carboxylic acid 
• 1383733-71-8 1-(4-fluorophenyl)-l,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4,6-dicarboxylic acid 4-{[(S)-1-(2-methanesulfonyl-pyridin-4-yl)-butyl]-amide} 6-methylamide 

Relevant academic research and scientific papers

FIVE-MEMBER-HETEROCYCLE FUSED PYRIDINE COMPOUNDS, METHOD OF PRODUCING THE SAME, AND USE THEREOF

This invention provides a class of five-member-heterocycle fused pyridine compounds as shown below in Formula (X), pharmaceutically acceptable salts or pharmaceutically acceptable solvates thereof, a method of producing the same, pharmaceutical compositions containing the compound, and use of the compounds in preparing medicament for preventing and/or treating diseases and tumours associated with abnormal protein tyrosine kinase.

PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of using same.