1383745-37-6

Basic information

• Product Name: N-(2,6-difluoro-3-(propylsulfonamido)phenyl)acetamide
• Synonyms: N-(2,6-difluoro-3-(propylsulfonamido)phenyl)acetamide
• CAS NO: 1383745-37-6
• Molecular Weight: 292.307
• Mol File: 1383745-37-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-(2,6-difluoro-3-(propylsulfonamido)phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-difluoro-3-(propylsulfonamido)phenyl)acetamide(1383745-37-6)
• EPA Substance Registry System: N-(2,6-difluoro-3-(propylsulfonamido)phenyl)acetamide(1383745-37-6)

Safety Data

• Hazardous Substances Data: 1383745-37-6(Hazardous Substances Data)

Upstream product

• 10147-36-1 n-propanesulfonyl chloride 
• 946826-47-7 N-(3-amino-2,6-difluorophenyl)acetamide 
• 3896-29-5 N-(2,6-difluorophenyl)acetamide 
• 25892-08-4 N-(2,6-difluoro-3-nitrophenyl)acetamide 
• 5509-65-9 2,6-difluoroaniline 

Downstream Products

• 1383745-19-4 C₉H₁₂F₂N₂O₂S*ClH 
• 1380228-04-5 N-(3-(3-(9H-purine-6-yl)pyridin-2-ylamino)-2,4-difluorophenyl) propane-1-sulfonamide 
• 1380228-80-7 N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)propane-1-sulfonamide 
• 1392429-79-6 N-(3-(5-((1-ethylpiperidin-4-yl)(methyl)amino)-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin- 1-yl)-2,4-difluorophenyl)propane-1-sulfonamide 
• 1383745-23-0 C₉H₁₀F₂N₄O₂S 
• 1383744-76-0 C₂₃H₂₅F₂N₇O₂S 
• 1383744-75-9 C₂₂H₂₄F₂N₈O₂S 
• 1383744-74-8 C₂₃H₂₇F₂N₇O₃S 
• 1383744-73-7 C₂₀H₂₃F₂N₇O₂S 
• 1383744-72-6 C₂₅H₃₁F₂N₇O₄S 
• 1383744-71-5 C₂₁H₂₁F₂N₇O₂S 
• 1383744-66-8 C₂₁H₂₃F₂N₅O₄S 
• 1383744-41-9 C₂₅H₃₁F₂N₇O₃S 
• 1383744-40-8 C₁₆H₁₄BrF₂N₅O₂S 

Relevant articles and documents

CRYSTALLINE SALTS OF A B-RAF KINASE INHIBITOR

The present invention is related to crystalline salts of N-(3-(5-((1-ethylpiperidin-4-yl)(methyl)amino)-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl)-2,4-difluorophenyl)propane-1-sulfonamide, a RAF kinase Inhibitor, useful in the treatment of cancer and other diseases.

PYRIMIDO[5,4-D]PYRIMIDYLAMINO PHENYL SULFONAMIDES AS SERINE/THREONINE KINASE INHIBITORS

The present invention encompasses compounds of general formula (I) wherein the groups R2 to R4 and X are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain compounds of this kind and their use as medicaments.

NEW TRIAZOLYLPHENYL SULFONAMIDES AS SERINE/THREONINE KINASE INHIBITORS

The present invention encompasses compounds of general formula (I) wherein the groups R2 to R4, A,X and m are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain compounds of this kind and their use as medicaments.