13838-44-3

Basic information

• Product Name: 5-Methoxy-7-nitro-1H-indole-2-carboxylic acid ethyl ester
• Synonyms: 5-Methoxy-7-nitro-1H-indole-2-carboxylic acid ethyl ester
• CAS NO: 13838-44-3
• Molecular Formula: C12H12N2O5
• Molecular Weight: 264.238
• Mol File: 13838-44-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-Methoxy-7-nitro-1H-indole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxy-7-nitro-1H-indole-2-carboxylic acid ethyl ester(13838-44-3)
• EPA Substance Registry System: 5-Methoxy-7-nitro-1H-indole-2-carboxylic acid ethyl ester(13838-44-3)

Safety Data

• Hazardous Substances Data: 13838-44-3(Hazardous Substances Data)

Upstream product

• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 96-96-8 4-methoxy-2-nitroaniline 
• 13838-43-2 ethyl 2-(2-(4-methoxy-2-nitrophenyl)hydrazono)propanoate 

Downstream Products

• 13838-45-4 5-methoxy-7-nitro-1H-indole-2-carboxylic acid 
• 10553-10-3 5-methoxy-7-nitro-1H-indole 

Relevant articles and documents

An unusual product in a Doebner-von Miller quinoline synthesis

In an attempt to synthesize an aza pyrroloquinolinequinone isomer, Doebner-von Miller quinoline synthesis from an aminoindole resulted in an unexpected product, formed by reaction at an electron-rich benzenoid carbon with the unsaturated carbon atom β to the ketone of dimethyl trans-2- oxoglutaconate. This observation suggests an alternative mechanistic possibility for Doebner-von Miller reaction with some electron-rich aromatic amines.

Perenosins: A new class of anion transporter with anti-cancer activity

A new class of anion transporter named 'perenosins' consisting of a pyrrole linked through an imine to either an indole, benzimidazole or indazole is reported. The indole containing members of the perenosin family function as effective transmembrane Cl-/NO3- antiporters and HCl cotransporters in a manner similar to the prodigiosenes. The compounds reduce the viability of MDA-MB-231 and MCF-7.